{"key":"op_293_ES","page":{"url":"https://jp.bookimed.com/clinics/country=spain/procedure=hyperthermic-intraperitoneal-chemotherapy/","procedure":{"id":293,"slug":"hyperthermic-intraperitoneal-chemotherapy","name":"腹腔内温熱化学療法","name_forms":{"plural":{"status":"missing","reason":"not_collected"},"genitive":{"status":"missing","reason":"not_collected"}},"type":"surgery","grammar_number":{"status":"missing","reason":"not_collected"},"parent_id":"oncology","family_attribute":{"status":"missing","reason":"not_collected"}},"country":{"id":34,"iso":"ES","name":"スペイン"},"currency":"USD","data_date":{"status":"missing","reason":"not_collected"}},"pages":{"clinics_url":"https://jp.bookimed.com/clinics/country=spain/procedure=hyperthermic-intraperitoneal-chemotherapy/","cost_url":"https://jp.bookimed.com/clinics/country=spain/procedure=hyperthermic-intraperitoneal-chemotherapy/cost/","best_url":{"status":"missing","reason":"template not live"}},"price":{"from":21800,"to":31000,"avg":{"value":21634,"method":"median","source":"offers"},"us":{"from":75000,"to":120000},"uk":{"from":38000,"to":68000},"by_technique":{"status":"missing","reason":"not_collected"},"by_city":[{"city":"マドリード","from":21800},{"city":"アリカンテ","from":16500},{"city":"バルセロナ","from":24000}],"per_unit":{"status":"missing","reason":"not_collected"},"factors":{"status":"missing","reason":"not_collected"},"tiers":{"source":"offers","items":[{"tier":"premium","min":21634,"max":21634,"median":21634,"count":1}]},"comparison":[{"country_iso":"UA","from":6500,"to":11000},{"country_iso":"FR","from":22000,"to":34000},{"country_iso":"GB","from":38000,"to":68000},{"country_iso":"US","from":75000,"to":120000},{"country_iso":"IL","from":60000,"to":65000},{"country_iso":"TR","from":18000,"to":26500},{"country_iso":"MX","from":18000,"to":30000},{"country_iso":"DE","from":40000,"to":52000},{"country_iso":"CA","from":52000,"to":85000},{"country_iso":"AE","from":24000,"to":38000},{"country_iso":"TH","from":13500,"to":22000},{"country_iso":"PL","from":14000,"to":24000},{"country_iso":"KR","from":18000,"to":45000},{"country_iso":"CZ","from":14000,"to":23000},{"country_iso":"AT","from":24000,"to":37000},{"country_iso":"IT","from":21000,"to":32000},{"country_iso":"CN","from":9000,"to":19000},{"country_iso":"AU","from":48000,"to":70000},{"country_iso":"IN","from":15000,"to":17000},{"country_iso":"MY","from":14000,"to":23000},{"country_iso":"VN","from":9500,"to":16500},{"country_iso":"BR","from":16000,"to":27000},{"country_iso":"AZ","from":7400,"to":13000}],"base_country":"US","base_is_fallback":false},"savings":{"pct":71,"variant":">=15%"},"package":{"included":["24-hr nurse services","Consultation with a surgeon","Consultation with an anesthesiologist","Hospitalization","Transfer to the clinic"],"excluded":{"status":"missing","reason":"not_collected"},"extra_charges":{"status":"missing","reason":"not_collected"}},"clinics":{"count":5,"items":[{"id":78,"name":"Centro Médico Teknon","city":"Barcelona","rating":4.7,"reviews_count":497,"accreditations":["Joint Commission International","European Foundation for Quality Management","THE IMTJ MEDICAL TRAVEL AWARD WINNER IN 2019","Patient choice in Neurology","Patient choice in Neurosurgery","Patient choice for Epilepsy treatment","World's Best Hospitals 2021 by Newsweek"],"rank":1,"has_procedure":true,"why_ranked":"Clinic has a specialized Peritoneal Oncology Surgery Unit with doctors trained by Dr. Paul Sugarbaker. 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Why: the operation is complex, so experience matters","scope":"procedure","source":{"url":"https://stonybrookmedicine.edu/node/2289","host":"stonybrookmedicine.edu","quote":"Patients should seek surgeons with established track records of performing these complex operations.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C2","text":"Check the qualifications of the medical team that will treat you","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"Have you checked the qualifications of the medical team treating you?","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C3","text":"Get a second opinion from a doctor at home on whether the treatment is necessary and what options exist","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"A doctor can give you a valuable second opinion as well as advice about treatment options and whether it's necessary.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C4","text":"Find out whether follow-up care is scheduled at the same facility as the procedure","scope":"treatment_abroad","source":{"url":"https://www.cdc.gov/yellow-book/hcp/health-care-abroad/medical-tourism.html","host":"cdc.gov","quote":"Medical tourists should also know whether follow-up care is scheduled to occur at the same facility as the procedure.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":403}},{"id":"C5","text":"Confirm the surgeon is trained and experienced in the exact procedure you are considering, not just in surgery generally","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Verify that the surgeon is trained and experienced in performing the procedure you are considering.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"Pressure to make a quick decision about booking treatment abroad","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"pressure to make a quick decision","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F2","text":"Booking advice from sales staff or travel agents is a red flag","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Do not accept advice from a travel agent, sales representatives or administrators.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F3","text":"Being unable to speak directly with the treating clinician before booking is a red flag","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Speak directly to the doctor, dentist or nurse who will be carrying out your treatment before you book your trip.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F4","text":"Being denied the chance to change your mind during the consultation is a red flag","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"You should be given the opportunity to change your mind during this consultation.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"warning_signs":{"status":"ok","items":[{"id":"W1","text":"Severe swelling, warmth or drainage at the incision","urgency":"contact_clinic","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/21569-hyperthermic-intraperitoneal-chemotherapy-hipec","host":"my.clevelandclinic.org","quote":"Severe swelling, warmth or drainage around your incision site","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W2","text":"Nausea and vomiting that do not 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gp","source":{"url":"https://www.nhs.uk/nhs-services/hospitals/going-into-hospital/being-discharged-from-hospital","host":"nhs.uk","quote":"You'll also be given a letter for your GP, providing information about your treatment and future care needs.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"T2","text":"Ask for written details of the procedure before you leave the hospital","document":"written procedure details","source":{"url":"https://rcseng.ac.uk/patient-care/cosmetic-surgery/after-surgery/","host":"rcseng.ac.uk","quote":"After your surgery, before you leave the hospital, ask for written information about the procedure you've had.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T3","text":"Ask for copies of all prescriptions before you leave","document":"prescription copies","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Remember to ask for copies of all your treatment records, including prescriptions, scans and x-rays before you leave.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T4","text":"Home doctor needs the dates for required blood tests and follow-up appointments","document":"written aftercare plan","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"This should include any medication and doses, as well as any dates that blood tests and follow-up appointments must be carried out.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1}},"parsed_details":{"procedure_type":"surgery","fields":{"anesthesia":["general"],"back_to_work_days":{"min":60,"max":120,"unit":"days","qualifier":"After cytoreductive surgery with HIPEC; depends on extent of surgery, complications, adjuvant chemotherapy 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optimisation","Anaesthetic and ICU planning","Fasting and bowel preparation as instructed","Stoma counselling where relevant","Smoking cessation and informed consent"],"recovery_timeline":[{"phase":"Days 0-3","description":"ICU or high-dependency monitoring, pain control, fluid and electrolyte management.","restrictions":["Bed rest with assisted mobilisation","Nothing by mouth initially"]},{"phase":"Days 4-21","description":"Gradual return of bowel function and diet, drain removal, mobilisation, discharge when stable.","restrictions":["No lifting","Dietary progression"]},{"phase":"Weeks 3-8","description":"Home recovery, fatigue improving, wound healing, nutrition rebuilding; possible adjuvant chemotherapy planning.","restrictions":["Avoid heavy lifting and strenuous activity"]},{"phase":"Months 2-4","description":"Return to ordinary activities and work for many patients; start of surveillance.","restrictions":["Gradual increase in activity as tolerated"]}],"rehabilitation_days":{"min":42,"max":90,"unit":"days","qualifier":"Ordinary functional recovery after cytoreductive surgery with HIPEC; fatigue may persist longer."},"result_longevity":"Benefit is disease control, not cure for all. Durability varies by tumour type and completeness of cytoreduction; some patients remain disease-free for years, others recur and need surveillance.","revision_rate_pct":{"min":5,"max":15,"unit":"percent","qualifier":"Unplanned return to theatre within 30-90 days, e.g. for leak, bleeding or abscess"},"scars":"Long midline abdominal incision (xiphoid to pubis) is typical, plus drain sites; a stoma may be needed in some patients.","sessions_or_stages":{"sessions":{"min":1,"max":1,"unit":"visits","qualifier":"One combined operation: cytoreductive surgery followed by HIPEC perfusion."},"stages":[{"code":"cytoreduction","label":"Cytoreductive surgery removing visible tumour and affected tissue","after":{"min":0,"max":0,"unit":"days","qualifier":"Same operation"}},{"code":"hipec_perfusion","label":"Heated intraperitoneal chemotherapy perfusion (typically 30-90 minutes)","after":{"min":0,"max":0,"unit":"days","qualifier":"Same operation, after cytoreduction"}},{"code":"reconstruction","label":"Bowel reconstruction or closure","after":{"min":0,"max":0,"unit":"days","qualifier":"Same operation"}}],"qualifier":"Single operative session with sequential stages."},"success":{"metric":"5-year overall survival after complete cytoreduction with HIPEC","value":50,"unit":"percent","horizon":"5 years","population":"Adults with peritoneal metastases, mixed tumour types, complete or near-complete cytoreduction","evidence_status":"limited"},"techniques":[{"name":"Open (coliseum) HIPEC with cytoreductive surgery","suits_whom":"Patients with peritoneal surface malignancy where abdomen is kept open during perfusion for uniform heat distribution and surgeon access.","recovery":"Inpatient stay of about 10-21 nights; recovery over several weeks to months."},{"name":"Closed-abdomen HIPEC with cytoreductive surgery","suits_whom":"Patients with peritoneal surface malignancy where the abdomen is closed before perfusion to maintain temperature and reduce exposure.","recovery":"Similar to open technique: about 10-21 nights inpatient and recovery over weeks to months."}],"treatment_conditions":["inpatient"],"treatment_duration_hours":{"min":6,"max":12,"unit":"hours","qualifier":"Complete operation, cytoreductive surgery plus HIPEC perfusion; varies with disease extent."},"initial_assessment_documents":["Histopathology report of primary tumour or biopsy","Contrast CT of chest, abdomen and pelvis","Abdominopelvic MRI report","Tumour marker blood results","Previous operative and chemotherapy reports","Recent kidney and liver function blood tests"],"travel_trips":{"min":1,"max":1,"one_trip_possible":true,"qualifier":"Single combined operation; about 10-21 nights inpatient until discharge and fitness to fly. Surveillance usually at home."},"clinic_checks":{"status":"ok","items":[{"id":"C1","text":"Check the surgeon's established track record with these complex operations. Why: the operation is complex, so experience matters","scope":"procedure","source":{"url":"https://stonybrookmedicine.edu/node/2289","host":"stonybrookmedicine.edu","quote":"Patients should seek surgeons with established track records of performing these complex operations.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C2","text":"Check the qualifications of the medical team that will treat you","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"Have you checked the qualifications of the medical team treating you?","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C3","text":"Get a second opinion from a doctor at home on whether the treatment is necessary and what options exist","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"A doctor can give you a valuable second opinion as well as advice about treatment options and whether it's necessary.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"C4","text":"Find out whether follow-up care is scheduled at the same facility as the procedure","scope":"treatment_abroad","source":{"url":"https://www.cdc.gov/yellow-book/hcp/health-care-abroad/medical-tourism.html","host":"cdc.gov","quote":"Medical tourists should also know whether follow-up care is scheduled to occur at the same facility as the procedure.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":403}},{"id":"C5","text":"Confirm the surgeon is trained and experienced in the exact procedure you are considering, not just in surgery generally","scope":"treatment_abroad","source":{"url":"https://www.isaps.org/discover/patients-home/considering-your-procedure-abroad/finding-a-surgeon-abroad/","host":"isaps.org","quote":"Verify that the surgeon is trained and experienced in performing the procedure you are considering.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"red_flags":{"status":"ok","items":[{"id":"F1","text":"Pressure to make a quick decision about booking treatment abroad","scope":"treatment_abroad","source":{"url":"https://www.nhs.uk/using-the-nhs/healthcare-abroad/going-abroad-for-treatment/treatment-abroad-checklist/","host":"nhs.uk","quote":"pressure to make a quick decision","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F2","text":"Booking advice from sales staff or travel agents is a red flag","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Do not accept advice from a travel agent, sales representatives or administrators.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F3","text":"Being unable to speak directly with the treating clinician before booking is a red flag","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Speak directly to the doctor, dentist or nurse who will be carrying out your treatment before you book your trip.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"F4","text":"Being denied the chance to change your mind during the consultation is a red flag","scope":"treatment_abroad","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"You should be given the opportunity to change your mind during this consultation.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"warning_signs":{"status":"ok","items":[{"id":"W1","text":"Severe swelling, warmth or drainage at the incision","urgency":"contact_clinic","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/21569-hyperthermic-intraperitoneal-chemotherapy-hipec","host":"my.clevelandclinic.org","quote":"Severe swelling, warmth or drainage around your incision site","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W2","text":"Nausea and vomiting that do not improve","urgency":"contact_clinic","general":false,"source":{"url":"https://my.clevelandclinic.org/health/treatments/21569-hyperthermic-intraperitoneal-chemotherapy-hipec","host":"my.clevelandclinic.org","quote":"Nausea and vomiting that don’t improve","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"W3","text":"Fever above 101 degrees F (38.3 degrees C)","urgency":"contact_clinic","general":true,"source":{"url":"https://my.clevelandclinic.org/health/treatments/21569-hyperthermic-intraperitoneal-chemotherapy-hipec","host":"my.clevelandclinic.org","quote":"Fever above 101 degrees F (38.3 degrees C)","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"take_home":{"status":"ok","items":[{"id":"T1","text":"Gives the home doctor treatment details and future care needs","document":"discharge letter for gp","source":{"url":"https://www.nhs.uk/nhs-services/hospitals/going-into-hospital/being-discharged-from-hospital","host":"nhs.uk","quote":"You'll also be given a letter for your GP, providing information about your treatment and future care needs.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},{"id":"T2","text":"Ask for written details of the procedure before you leave the hospital","document":"written procedure details","source":{"url":"https://rcseng.ac.uk/patient-care/cosmetic-surgery/after-surgery/","host":"rcseng.ac.uk","quote":"After your surgery, before you leave the hospital, ask for written information about the procedure you've had.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T3","text":"Ask for copies of all prescriptions before you leave","document":"prescription copies","source":{"url":"https://travelhealthpro.org.uk/news/699/travelling-abroad-for-treatment","host":"travelhealthpro.org.uk","quote":"Remember to ask for copies of all your treatment records, including prescriptions, scans and x-rays before you leave.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}},{"id":"T4","text":"Home doctor needs the dates for required blood tests and follow-up appointments","document":"written aftercare plan","source":{"url":"https://sbuhb.nhs.wales/about-us/individual-patient-commissioning/ipc-folder/advice-on-accessing-treatment-abroad","host":"sbuhb.nhs.wales","quote":"This should include any medication and doses, as well as any dates that blood tests and follow-up appointments must be carried out.","tier":"tier1_medical","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"alternatives":{"status":"ok","items":[{"id":"A1","text":"You would rather have several rounds of chemotherapy","name":"Systemic chemotherapy","source":{"url":"https://my.clevelandclinic.org/health/treatments/21569-hyperthermic-intraperitoneal-chemotherapy-hipec","host":"my.clevelandclinic.org","quote":"With systemic chemotherapy, treatment usually involves several sessions, or “rounds,” of chemotherapy.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200},"operation_id":null},{"id":"A2","text":"You want the standard surgery and IV chemotherapy option","name":"Surgery and IV chemotherapy","source":{"url":"https://www.healthline.com/health/cancer/hyperthermic-intraperitoneal-chemotherapy","host":"healthline.com","quote":"multiple studies have found that HIPEC has no greater benefit than the current standard of care (surgery and IV chemotherapy).","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200},"operation_id":null}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"technique_details":{"status":"ok","items":[{"id":"open-hipec","name":"Open (coliseum) HIPEC with cytoreductive surgery","how_it_works":{"text":"Surgeons remove visible abdominal tumors before heated chemotherapy treats remaining cancer cells","source":{"url":"https://my.clevelandclinic.org/departments/digestive/depts/hipec","host":"my.clevelandclinic.org","quote":"First, your surgeon removes any visible tumors from the abdomen.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"}},{"id":"closed-abdomen-hipec","name":"Closed-abdomen HIPEC with cytoreductive surgery","how_it_works":{"text":"Heated chemotherapy treats remaining abdominal cancer cells after visible tumors are removed","source":{"url":"https://my.clevelandclinic.org/departments/digestive/depts/hipec","host":"my.clevelandclinic.org","quote":"HIPEC delivers heated chemotherapy directly inside the abdomen to help destroy any remaining cancer cells and very small tumors that cannot be seen by the surgeon.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"}}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1}}},"techniques":[{"id":"open-hipec","name":"Open (coliseum) HIPEC with cytoreductive surgery","how_it_works":{"id":"H1","text":"Surgeons remove visible abdominal tumors before heated chemotherapy treats remaining cancer cells","source":{"url":"https://my.clevelandclinic.org/departments/digestive/depts/hipec","host":"my.clevelandclinic.org","quote":"First, your surgeon removes any visible tumors from the abdomen.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"},"suits_whom":"Patients with peritoneal surface malignancy where abdomen is kept open during perfusion for uniform heat distribution and surgeon access.","price_from":{"status":"missing","reason":"not_collected"},"recovery":"Inpatient stay of about 10-21 nights; recovery over several weeks to months."},{"id":"closed-abdomen-hipec","name":"Closed-abdomen HIPEC with cytoreductive surgery","how_it_works":{"id":"H1","text":"Heated chemotherapy treats remaining abdominal cancer cells after visible tumors are removed","source":{"url":"https://my.clevelandclinic.org/departments/digestive/depts/hipec","host":"my.clevelandclinic.org","quote":"HIPEC delivers heated chemotherapy directly inside the abdomen to help destroy any remaining cancer cells and very small tumors that cannot be seen by the surgeon.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200}},"recovery_daily":{"status":"missing","reason":"no_official_source"},"suits_whom":"Patients with peritoneal surface malignancy where the abdomen is closed before perfusion to maintain temperature and reduce exposure.","price_from":{"status":"missing","reason":"not_collected"},"recovery":"Similar to open technique: about 10-21 nights inpatient and recovery over weeks to months."}],"alternatives":{"status":"ok","items":[{"id":"A1","text":"You would rather have several rounds of chemotherapy","name":"Systemic chemotherapy","source":{"url":"https://my.clevelandclinic.org/health/treatments/21569-hyperthermic-intraperitoneal-chemotherapy-hipec","host":"my.clevelandclinic.org","quote":"With systemic chemotherapy, treatment usually involves several sessions, or “rounds,” of chemotherapy.","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200},"operation_id":null},{"id":"A2","text":"You want the standard surgery and IV chemotherapy option","name":"Surgery and IV chemotherapy","source":{"url":"https://www.healthline.com/health/cancer/hyperthermic-intraperitoneal-chemotherapy","host":"healthline.com","quote":"multiple studies have found that HIPEC has no greater benefit than the current standard of care (surgery and IV chemotherapy).","tier":"tier1_medical","fetched_at":"2026-11-12","http_status":200},"operation_id":null}],"checked_at":"2026-11-12","next_check_at":"2027-11-12","version":1},"diagnostic":{"status":"not_applicable"},"country":{"why":{"status":"missing","reason":"no_official_source","checked_at":"2026-11-11","next_check_at":"2027-02-09"},"travel":{"status":"ok","items":[{"id":"V1","item":"passport_validity","audience":"uk","volatile":true,"text":"The passport must have an expiry date at least 3 months after you plan to leave the Schengen area","source":{"url":"https://www.gov.uk/foreign-travel-advice/spain/entry-requirements","host":"gov.uk","quote":"have an ‘expiry date’ at least 3 months after the day you plan to leave the Schengen area (the expiry date does not need to be within 10 years of the date of issue)","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V2","item":"medicines","audience":"all","volatile":false,"text":"Carry prescription medication in its original packaging, along with your doctor's prescription","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Spain.html","host":"travel.state.gov","quote":"Always carry your prescription medication in original packaging, along with your doctor’s prescription.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V3","item":"prescriptions","audience":"us","volatile":false,"text":"Medications that require a prescription in the United States also require a local doctor's prescription in Spain","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Spain.html","host":"travel.state.gov","quote":"Medications requiring prescriptions in the United States also require a local doctor’s prescription in Spain.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V4","item":"ghic","audience":"uk","volatile":false,"text":"A GHIC or EHIC is needed to get medically necessary state healthcare in Spain","source":{"url":"https://www.gov.uk/foreign-travel-advice/spain/health","host":"gov.uk","quote":"To get medically necessary state healthcare in Spain, you need a Global Health Insurance Card ( GHIC ) or a European Health Insurance Card ( EHIC ).","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}},{"id":"V5","item":"hospital_payment","audience":"all","volatile":false,"text":"Private hospitals usually require payment or proof of insurance or funds before admitting a patient","source":{"url":"https://travel.state.gov/content/travel/en/international-travel/International-Travel-Country-Information-Pages/Spain.html","host":"travel.state.gov","quote":"Private hospitals usually require payment or proof insurance or funds before admitting a patient.","tier":"official_travel","fetched_at":"2026-11-11","http_status":403}},{"id":"V6","item":"emergency_number","audience":"all","volatile":false,"text":"Dial 112 and ask for an ambulance","source":{"url":"https://www.gov.uk/foreign-travel-advice/spain/health","host":"gov.uk","quote":"Dial 112 and ask for an ambulance.","tier":"official_travel","fetched_at":"2026-11-11","http_status":200}}],"checked_at":"2026-11-11","next_check_at":"2026-12-11","version":1},"other_countries_with_page":["azerbaijan","china","germany","greece","india","israel","italy","malaysia","republic-of-korea","thailand","turkey","ukraine"]},"often_combined_with":{"status":"missing","reason":"not_collected"},"reviews":{"avg_rating":4.69,"count":506,"scope":"clinic","rating_scale":5,"pros":{"status":"missing","reason":"not_collected"},"cons":{"status":"missing","reason":"not_collected"}},"current":{"seo_text":"<p>Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Spain typically costs from _op_293_price_from_ to _op_293_price_to_. The final price depends on the peritoneal cancer index, surgical complexity, and the specific hospital tier. In the US, similar procedures cost around _price_compare_US_average_ on average. Spain offers savings of around _price_percent_discount_%. Common inclusions are pre-operative imaging, cytoreductive surgery, the HIPEC perfusion, and intensive care stays.</p>\n\n<ul>\n<li><strong>Hospital location:</strong> Packages in Barcelona and Madrid may cost 15-20% more than in regional hubs like Valencia.</li>\n<li><strong>Surgical complexity:</strong> Extensive disease requiring multi-organ resection increases the surgical time and overall procedure cost.</li>\n<li><strong>Robotic-assisted approach:</strong> Using robotic systems for the preceding surgery typically adds 20-30% to the total bill.</li>\n<li><strong>Post-operative care:</strong> Extended ICU monitoring beyond the standard two days will increase the final inpatient expenses.</li>\n</ul>\n\n<p><strong>Bookimed Expert Insight:</strong> Choosing a specialist like Dr. Lana Bijelic at Centro Médico Teknon provides world-class expertise. She trained under Prof. Paul Sugarbaker, the pioneer of the HIPEC technique. Patients benefit from JCI-accredited care in Barcelona at a mid-range European price point. This clinic is a top choice for complex cases, having treated celebrities and professional athletes.</p>","faq":[{"q":"What is HIPEC and how does it work?","a":"<p>Hyperthermic intraperitoneal chemotherapy (HIPEC) is a concentrated, heated chemotherapy treatment delivered directly into the abdominal cavity during surgery. It targets microscopic cancer cells remaining after a surgeon removes all visible tumors, significantly improving survival rates for advanced abdominal cancers like colorectal and ovarian malignancies.</p> <ul> <li><strong>Two-step process:</strong> Surgeons first perform cytoreductive surgery to remove all visible tumors.</li> <li><strong>Heated bath:</strong> Chemotherapy heated to 42°C (108°F) circulates for 30 to 90 minutes.</li> <li><strong>Enhanced penetration:</strong> Heat expands blood vessels, allowing drugs to penetrate tissues more effectively.</li> <li><strong>Reduced toxicity:</strong> Direct abdominal delivery limits systemic side effects common with intravenous chemotherapy.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Spain offers unique access to pioneers like Dr. Lana Bijelic at Centro Médico Teknon. She trained under Dr. Paul Sugarbaker, the father of the HIPEC procedure. Spanish centers often combine HIPEC with PIPAC (pressurized aerosol chemotherapy), providing more options for patients who may not tolerate traditional major surgery.</p> <p><strong>Patient Consensus:</strong> While patients report this procedure can be physically brutal with intense nausea, many view it as a life-extending standard for stage 4 cancer. Success stories include survivors reaching the 9-year mark after treatment.</p>"},{"q":"What is the success rate of HIPEC in Spain?","a":"<p>HIPEC success in Spain shows a median overall survival reaching 47 months in high-volume centers. Specialized institutions achieve complete cytoreduction in over 90% of cases. Outcomes depend on the Peritoneal Cancer Index, with best results observed when scores remain low, typically under 7.</p> <ul> <li><strong>Survival rates:</strong> Median disease-free survival is approximately 16 months in specialized Spanish oncology centers.</li> <li><strong>Success by type:</strong> Colorectal cancer patients often achieve median survival between 42 and 46 months.</li> <li><strong>Surgical efficacy:</strong> Surgeons successfully remove all visible tumors in 90% of selected clinical cases.</li> <li><strong>Safety metrics:</strong> Mortality rates for this complex procedure stay low, ranging between 2% and 3.4%.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Success in Spain is linked to doctors trained directly by pioneers like Dr. Paul Sugarbaker. Dr. Lana Bijelic at Centro Médico Teknon has performed over 1,300 complex cancer surgeries. This high volume directly correlates with the 90% complete cytoreduction rates seen in top Spanish hospitals.</p> <p><strong>Patient Consensus:</strong> Patients emphasize that success is highly individual and depends more on fitness than statistics. While recurrence is common, around 20% of patients achieve long-term survival lasting up to 9 years.</p>"},{"q":"Which cancers can be treated with HIPEC?","a":"<p>Hyperthermic intraperitoneal chemotherapy treats advanced cancers that have spread to the abdominal lining, specifically peritoneal carcinomatosis. This intensive therapy targets malignancies including ovarian, colorectal, gastric, and appendix cancers, alongside peritoneal mesothelioma and pseudomyxoma peritonei, by delivering heated drugs directly into the abdominal cavity after surgical tumor removal.</p> <ul> <li><strong>Gastrointestinal cancers:</strong> Effectively targets stage 4 colon, rectal, and advanced stomach (gastric) cancers.</li> <li><strong>Gynecologic malignancies:</strong> Primarily treats advanced or recurrent ovarian cancer to reduce recurrence risks.</li> <li><strong>Rare pathologies:</strong> Specialized for appendiceal cancer, primary peritoneal cancer, and asbestos-linked peritoneal mesothelioma.</li> <li><strong>Strict eligibility:</strong> Limited to patients whose cancer remains confined within the peritoneal cavity.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Spanish oncology centers often provide PIPAC alongside traditional HIPEC, offering a less invasive aerosolized alternative for patients with high-volume ascites. Dr. Alfonso García Fadrique at Hospital Vithas Valencia Turia leads specialized R&amp;D into HIPEC quality standards, which is a critical differentiator when choosing a center for such complex 12-hour surgeries.</p> <p><strong>Patient Consensus:</strong> Patients often view this procedure as a decisive first-line attack rather than a last resort. Many emphasize that while the 2-month recovery is demanding, the potential for remaining disease-free for several years makes the intensive surgery worthwhile.</p>"},{"q":"What are the best hospitals for HIPEC in Spain?","a":"<p>Top hospitals for HIPEC in Spain include Centro Médico Teknon in Barcelona and Hospital Ruber Internacional in Madrid. These JCI-accredited facilities specialize in cytoreductive surgery combined with heated chemotherapy. They feature surgeons trained by global pioneers to treat peritoneal carcinomatosis, pseudomyxoma peritonei, and advanced abdominal cancers.</p> <ul> <li><strong>Specialized expertise:</strong> Surgeons like Dr. Lana Bijelic trained under HIPEC pioneer Prof. Paul Sugarbaker.</li> <li><strong>Advanced technology:</strong> Facilities offer robotic Da Vinci Xi systems and pressurized aerosol chemotherapy (PIPAC).</li> <li><strong>Clinical trials:</strong> Quironsalud Madrid provides access to novel oncology trials for eligible cancer patients.</li> <li><strong>High-volume centers:</strong> Premier Spanish institutes perform over 170 complex peritoneal surgeries every year.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Data shows a significant experience gap in peritoneal oncology across Europe. At Centro Médico Teknon, Dr. Lana Bijelic has performed over 1,300 complex cancer surgeries. Choosing a surgeon with this specific volume is critical because HIPEC success depends heavily on the thoroughness of the initial debulking surgery.</p> <p><strong>Patient Consensus:</strong> Patients emphasize requesting a Peritoneal Carcinomatosis Index (PCI) score before surgery. They suggest preparing for a 2-week hospital stay and rigorous post-operative monitoring for bowel function recovery.</p>"},{"q":"Does HIPEC in Spain include aftercare?","a":"<p>HIPEC packages in Spain include essential clinical aftercare such as intensive care unit monitoring and specialized post-operative hospital stays. Treatment plans generally cover pre-operative imaging, cytoreductive surgery, and 7 to 10 days of inpatient stabilization to manage pain, nutrition, and digestive healing.</p> <ul> <li><strong>Hospital monitoring:</strong> Inpatient stay typically lasts 7 to 10 days for vital monitoring.</li> <li><strong>Intensive care:</strong> Initial recovery often begins in the ICU for specialized surgical oversight.</li> <li><strong>Nutritional support:</strong> Clinics provide intravenous nutrition or feeding tubes while the digestive tract heals.</li> <li><strong>Surgeon follow-up:</strong> Medical teams conduct multiple assessments to monitor recovery and manage incisions.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Quality aftercare in Spain is driven by high-volume surgical expertise. Dr. Lana Bijelic at Centro Médico Teknon has performed over 1,300 complex cancer surgeries, having trained under the pioneer of HIPEC. This level of specialization ensures that post-surgical protocols in Barcelona clinics are modeled after the world’s most successful peritoneal surface oncology programs.</p> <p><strong>Patient Consensus:</strong> Patients emphasize managing long-term recovery at home, noting that while hospital care is comprehensive, full normalization can take many months. Using low-fiber diets and staying extremely hydrated during the first few weeks after discharge are common practical recommendations.</p>"},{"q":"How long does the HIPEC procedure take?","a":"<p>The HIPEC procedure typically takes 90 minutes for the heated chemotherapy administration alone. However, when combined with cytoreductive surgery to remove visible tumors, the total operating time usually ranges from 9 to 14 hours in accredited Spanish oncology centers like Centro Médico Teknon.</p> <ul> <li><strong>Surgery duration:</strong> Cytoreductive surgery combined with HIPEC often lasts between 9 and 14 hours.</li> <li><strong>Chemotherapy phase:</strong> The heated chemotherapy wash specifically lasts about 90 minutes during the operation.</li> <li><strong>Tumor burden:</strong> Extensive cancer spread can push the total surgical time to 16 hours.</li> <li><strong>Previous surgeries:</strong> Scar tissue removal from prior operations can add 3 to 4 hours.</li> </ul> <p><strong>Bookimed Expert Insight:</strong> Data shows that surgical efficiency improves significantly during secondary procedures for recurrence. While initial surgeries often exceed 14 hours, follow-up procedures typically average 8 to 9.5 hours. Choosing a specialist like Dr. Lana Bijelic at Centro Médico Teknon, who has performed over 1,300 procedures, ensures expertise in managing these complex, high-volume timelines.</p> <p><strong>Patient Consensus:</strong> Patients emphasize that the physical toll is high, requiring 7 to 14 days of hospitalization. Most realize that full energy levels only return around 8 months after the procedure.</p>"},{"q":"What is the recovery time after HIPEC?","a":"<p>Recovery after HIPEC in Spain typically requires 3 to 6 months for returning to daily activities and up to 12 months for full functional restoration. This major procedure involves a 7 to 14-day hospital stay including intensive care monitoring and specialized oncology nursing.</p><ul><li><strong>Initial mobilization:</strong> Patients usually stand and sip liquids by day 3 post-surgery.</li><li><strong>Hospital duration:</strong> Most stays last 10 to 14 days in JCI-accredited Spanish facilities.</li><li><strong>Dietary transition:</strong> Patients generally begin eating solid foods between days 4 and 7.</li><li><strong>Work timeline:</strong> Desk-based professionals often return part-time around week 10.</li></ul><p><strong>Bookimed Expert Insight:</strong> While many assume the 90-minute heated chemotherapy causes the long recovery, the preceding cytoreductive surgery actually drives the timeline. Surgeons like Dr. Lana Bijelic at Centro Médico Teknon, who has performed 1,300+ complex cases, emphasize that recovery depends on the extent of organ resection rather than the chemo bath itself.</p><p><strong>Patient Consensus:</strong> Many describe the first month as physically demanding due to intense fatigue. Practical advice from others highlights the necessity of small, frequent meals and early physiotherapy to safely strengthen the core after abdominal surgery.</p>"}],"h2":[{"text":"仕組みについて","kind":"content"},{"text":"スペインでの腹腔内温熱化学療法費用について今すぐご確認ください","kind":"content"},{"text":"11月 2026のスペインでの特別腹腔内温熱化学療法プランをお見逃しなく","kind":"content"},{"text":"スペインの最高の腹腔内温熱化学療法クリニックをご発見ください：5件の認証済み選択肢と料金","kind":"content"},{"text":"スペインでの腹腔内温熱化学療法概要","kind":"content"},{"text":"スペインでの腹腔内温熱化学療法医療診断をお受けください：8名の経験豊富な医師に今すぐご相談","kind":"content"},{"text":"Bookimed患者のビデオストーリー","kind":"content"},{"text":"Bookimedに関するレビュー：患者様の洞察を発見","kind":"content"},{"text":"このコンテンツを共有","kind":"content"},{"text":"スペインでの腹腔内温熱化学療法に関するFAQ","kind":"content"},{"text":"無料相談を受ける","kind":"content"}]},"placeholders":{"price_from":"{{price_from}}","clinics_count":"{{clinics_count}}","cities_count":"{{cities_count}}","savings_pct":"{{savings_pct}}","data_date":"{{data_date}}"},"legal":{"restricted_markets":{"status":"missing","reason":"not_collected"}},"conflicts":[]}