Dr. Klaus D. Diemel is the Head of the Thoracic Surgery Department at Asklepios Klinik Barmbek, Hamburg and a Fellow of the European Board of Thoracic and Cardiovascular Surgeons. He has held senior positions at Krankenhaus Großhansdorf and Marienkrankenhaus Hamburg, and is a member of several national and international surgical and medical societies.
Senior surgeon of the “Gastrointestinal Medicine: General and Abdominal Surgery – Gastroenterology and Endoscopy” Department
Dr. Baha Zengel is a general surgeon with expertise in breast, gallbladder, thyroid diseases, and hernia repairs. He graduated from Ege University Faculty of Medicine in 1990. In 2004, he earned a doctorate in Basic Oncology from Dokuz Eylül University. He became an Associate Professor of General Surgery in 2014 through the Inter-University Board.
Dr. Zengel is skilled in advanced surgical procedures. His experience includes skin and breast-conserving mastectomy, oncoplastic breast surgery, laparoscopic cholecystectomy, sentinel lymph node biopsy, and ROLL/SNOLL techniques. He has held important positions at Izmir Bozyaka Training and Research Hospital, including Education Officer.
He is a member of several professional associations. He serves on the Board of Directors of the Aegean Region Surgery Association and is a founding board member of the Basic Oncology Association.
Dr. Felix Dobritoiu is a thoracic surgeon at Ponderas Academic Hospital. He specializes in minimally invasive and robotic procedures for adults and children. He performs robotic thoracic surgery with the da Vinci Xi system. He also uses video-assisted thoracoscopic surgery (VATS), including uniportal VATS. These methods use small incisions for faster recovery.
His practice includes mediastinoscopy and bronchoscopy. He performs complex lung and mediastinal resections. He also offers sternochondroplasty (Nuss and reversed Nuss). In selected cases, he can perform minimally invasive procedures without postoperative pleural drainage.
Dr. Taylan Bükülmez is a radiation oncologist at Istinye University Liv Hospital Bahcesehir in Istanbul. He treats breast, prostate, lung, esophageal, and rectal cancers. He uses advanced radiation therapy methods for his patients.
Dr. Bükülmez received his medical degree from Pamukkale University. He completed his specialization at Akdeniz University. Since 2017, he has led the oncology team at Istinye University Liv Hospital. He is known for his focus on patient recovery and new cancer treatments. He has many years of experience at leading oncology centers in Turkey.
Head of the Gastroenterology Department
Chief Physician of Asklepios Radiant Oncology Department
PROFESSIONAL EXPERIENCE
2011-2012
Erzurum Koprukoyu State Hospital
Department: General Medicine
2012-2017
Istanbul University Cerrahpaşa Medical Faculty
Department: Internal Medicine
06/2017-10/2017
Istanbul Gaziosmanpasa Taksim Training and Research Hospital
Department: Internal Medicine
10/2017-11/2018
Istanbul University Istanbul Medical Faculty
Department: Allergy and Immunology Fellowship
2018/2022
Istanbul University Oncology Institute
Department: Medical Oncology Fellowship
2022-2023
Tekirdag City Hospital
Department: Medical Oncology Specialist
2023-present
Istanbul Medipol University Medipol Bahcelievler Private Hospital
Department: Medical Oncology Assoc. Prof.
EDUCATION
2005-2011
Medical Education
Sivas Cumhuriyet University Medical Faculty, Sivas, Turkey
2012-2017
Internal Medicine
Istanbul University Cerrahpaşa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey
2017-2018
Allergy-Immunology Fellowship
Istanbul University Istanbul Medical Faculty
Department of Internal Medicine, Division of Allergy and Immunology, Istanbul, Turkey
2018-2022
Medical Oncology Fellowship
Istanbul University Oncology Institute, Department of Medical Oncology, Istanbul, Turkey
2022
ESMO Board Certification in Medical Oncology
10th September 2022 in Paris, France.
2023
Medical Oncology Assoc. Prof.
Istanbul Medipol University Department of Medical Oncology, Istanbul, Turkey
INTERNATIONAL CLINICAL TRIALS:
1. Astefania - ROCHE
2. PFİZER
3. RECITE - AMGEN
4. NAVIGATE - BAYER
5. RUBY - Tesaro (PRA)
6. ENGOT-ov43/GOG-3036 - MSD
7. ASTRA ZENECA
8. ROSY-O - ASTRA ZENECA
INTERNATIONAL PUBLICATIONS
I. Published journal articles indexed by SCI, SSCI, and AHCI
Weekly Paclitaxel in Classic Kaposi Sarcoma
Carboplatin Desensitization in Ovarian Carcinoma
High-Dose Chemotherapy for Ewing’s Sarcoma
Multidrug Refractory TFE3(+) Renal Cell Carcinoma
Crizotinib Efficacy in NSCLC with MET Alterations
Clinicopathological Features in ALK Mutant NSCLC
PSMA-Based Tumor Burden in Prostate Cancer
Atezolizumab in Metastatic Urothelial Carcinoma
Pulmonary Sarcomatoid Carcinoma
Prognostic Factors in Atezolizumab-Treated Urothelial Carcinoma
Atezolizumab with Chemotherapy in Small Cell Lung Cancer
FOLFIRINOX vs. Gemcitabine + Nab-Paclitaxel in Pancreatic Cancer
Trastuzumab Emtansine in Older HER2-Positive Breast Cancer Patients
Real-Life Efficacy of Osimertinib in Advanced NSCLC
ALK-Positive Cells Percentage and Alectinib Efficacy
Real-World Data on Alectinib in ALK-Positive NSCLC
Prognostic Factors in Metastatic RCC with T790M Mutation
FLOT Regimen in Metastatic Gastric Cancer
Desensitization Protocol in Lenalidomide Hypersensitivity Reactions
Factors Associated with Diagnostic Skin Test Positivity in PPI Hypersensitivity
Efficacy of Capecitabine and Temozolomide in Neuroendocrine Tumors
Subsequent Treatments in Hormone-Positive Breast Cancer Progression
Termination of Trastuzumab in HER2-Positive Metastatic Breast Cancer
Long-term Outcomes and Predictors of Recurrence in Node-Negative Early Stage Breast Cancer
Prognostic Factors Influencing PFS in HER2-Positive Metastatic Breast Cancer
Treatment Efficacy of Ribociclib or Palbociclib plus Letrozole in Metastatic Breast Cancer
Efficacy and Safety of Sorafenib in Adult Metastatic Osteosarcoma Patients
Single-Agent Temozolomide as Salvage Therapy in Heavily Pretreated Metastatic Sarcoma Patients
Outcomes and Prognostic Factors in Metastatic Renal Cell Carcinoma with Brain Metastases
FLOT Regimen in First-Line Treatment of Metastatic Gastric Cancer
Prognostic Factors of Perioperative FLOT Regimen in Operable Gastric Cancer
Efficacy and Outcomes of Systemic Chemotherapy in Posttransplant Kaposi Sarcoma
Comparison of Second-Line Treatments in Metastatic Renal Cell Carcinoma
Toxicity Management and Effectiveness of Regorafenib in Advance GIST Patients: A Real-world Study - Authors: Paksoy, N., Ferhatoğlu, F., Doğan, İ., Khanmammadov, N., Bozbey, H. U., Karabulut, S., & Taştekin, D. - Journal: TURKISH JOURNAL OF ONCOLOGY, 1(1)
Demographic and Clinical Features and Factors Associated with Survival in Patients with Primary Glomerulonephritis: Single Tertiary Center Experience - Authors: Paksoy, N., Trabulus, S., Seyahi, N., & Altiparmak, M. R. - Journal: Namik Kemal Tip Dergisi, 11(1)
Efficacy of Sorafenib in Symptomatic Patients with Pretreated Progressive Desmoid Tumors - Authors: Paksoy, N., Ferhatoglu, F., Dogan, I., Ak, N., Pehlivan, M., Ekenel, M., & Basaran, M.
Nodal Response to Neoadjuvant Chemotherapy is a Better Predictive Factor of Survival Than Miller-Payne Scoring in Breast Cancer - Authors: Ak, Naziye, et al. - Journal: Journal of Oncological Sciences, 7.2: 42-49
Evaluation of Prognostic and Predictive Values of Hemogram Parameters in Patients with Advanced Stage Ovarian Carcinoma - Authors: Ak, Naziye, et al. - Journal: Turkish Journal of Oncology/Türk Onkoloji Dergisi, 2021, 36.4
Identifying Risk Factors Associated with Survival and Drug-Related Toxicities in Imatinib-Resistant Gastrointestinal Stromal Tumor (GIST) Patients Treated with Sunitinib - Authors: Ferhatoglu, F., Karabulut, S., Paksoy, N., & Tastekin, D.
Real-life Outcomes of ROS1 Fusion-positive Metastatic Lung Cancer Patients who were Treated with Crizotinib - Authors: Dogan, İ., Khanmammadov, N., Paksoy, N., Ferhatoglu, F., Aydın, E., Vatansever, S., & Aydine, A. - Journal: TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY
Predictors of the acquisition of T790M mutation in EGFR-mutant metastatic lung cancer patients who were treated with EGFR inhibitors - Authors: Dogan, I., Khanmammadov, N., Paksoy, N., Vatansever, S., Saip, P., & Aydıner, A. - Journal: Eurasian Journal of Pulmonology
Laterality of Adrenal Gland Metastasis in Lung Cancer: Results of a Comparative Study - Authors: Ferhatoglu, F., Gagatay, T., Okumus, G., Aydiner, A., Paksoy, N., Ak, N., ... & Saip, P. - Journal: Eurasian Journal of Medical Investigation, 7(2)
Poor Risk Factors Affecting Cancer Patients Infected with Covid-19: A Retrospective Comparative Study from a Pandemic Hospital - Authors: Ferhatoglu, F., Kapağan, T., Paksoy, N., Ak, N., Medetalibeyoğlu, A., Şenkal, N., ... & Vatansever, S. - Journal: Turk Onkoloji Dergisi, 38(1)
Systemic Treatment Outcomes of Progressive Medullary Thyroid Carcinoma from the Registries of a Tertiary Cancer Center - Authors: Ferhatoglu, F., Paksoy, N., & Başaran, M. - Journal: Namik Kemal Tip Dergisi, 10(4)
Evaluation of clinical features and risk factors related to late recurrence (> 5 years) in patients with breast cancer - Authors: Ferhatoglu, F., Aydiner, A., & Paksoy, N. - Journal: Journal of Surgery & Medicine (JOSAM), 6(12)
Assessing the Clinical Impact of Lutetium-177 DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) on Metastatic Neuroendocrine Tumors: A Multicenter Real-World Data from Türkiye
Thesis:
Istanbul University Cerrahpaşa Medical Faculty, Internal Medicine Department PAKSOY, Nail. Demographical, clinical characteristics and survival factors in patients withprimary glomerulonephritis: Cerrahpasa Medical Faculty Experience. (2016)
International Refereed Congress / Symposium Publications in Proceedings (ASCO/ESMO Abstracts)
Prognostic factors influencing progression-free survival in HER2 positive metastatic breast cancer patients who treated with lapatinib and capecitabine combination
Efficacy of regorafenib and 5-fluorouracil-based rechallenge treatment in the third-line treatment of metastatic colorectal cancer: A Turkish oncology group study
Long-term outcomes and predictors of recurrence in patients with early-stage node-negative breast cancer
Efficacy of temozolomide in pretreated patients with metastatic sarcoma
Efficacy of sorafenib in symptomatic patients with pretreated progressive desmoid tumors
Efficacy of sorafenib in heavily pretreated adult patients with metastatic osteosarcoma
Outcomes and prognostic factors in metastatic renal cell carcinoma patients with brain metastases
Association of response to first-line chemotherapy with the efficacy of atezolizumab in patients with metastatic urothelial carcinoma
Safety and survival in adult women with platinum-sensitive relapsed BRCA mutant ovarian cancer: A study of patients in Olaparib Turkey Early Access Program—LynTurk study
Atezolizumab in patients with metastatic urothelial carcinoma who have progressed after first-line chemotherapy: Results of real-life experiences
Assoc. Prof. Atakan Topçu, M.D., is a medical oncologist at Medipol University and Medipol Acıbadem Regional Hospital. He treats solid tumors, including lung, breast, colorectal, gastric, and neuroendocrine cancers. His work also covers targeted therapies, immunotherapy, geriatric oncology, and cancer-related malnutrition, cachexia, and sarcopenia.
He has authored more than 50 peer-reviewed papers. Recent work includes a 2024 Frontiers in Medicine study on geriatric syndromes and a 2023 Future Oncology paper on sarcopenia and anxiety in lung cancer. He has also published on the CONUT score in breast cancer and on malnutrition in HER2-negative metastatic gastric cancer.
Dr. Topçu serves on the Editorial Board of BMC Cancer. He is a member of the Turkish Society of Medical Oncology, ESMO, and the Turkish Geriatrics Society. Education and training: M.D., Uludağ University; residency in Internal Medicine, Marmara University; fellowship in Medical Oncology, Bezmialem Vakıf University.
Dr. Inta Jaunalksne is an experienced immunologist with more than 30 years in the field. She specializes in virotherapy. She graduated from Riga Medical Institute and completed an internship in Internal Medicine. Dr. Jaunalksne is recognized as an expert in immunology.
She leads the Clinical Immunology Center at Pauls Stradins Clinical University Hospital. Dr. Jaunalksne has played a key role in advancing virotherapy and immunological research. Her work has improved treatment results and introduced new therapies. She is well respected in clinical immunology.
Assoc. Prof. Dr. Özlem Köroğlu is a specialist in Physical Medicine and Rehabilitation at Memorial Ankara Hospital (2024–present). She previously served as a faculty member at Gaziler Physical Therapy and Rehabilitation Training and Research Hospital (2016–2024). She was Chief of the Physical Medicine and Rehabilitation Clinic at Elazığ Military Hospital (2011–2015). She earned her MD in 2003 from the GATA Faculty of Medicine. She completed her PM&R residency in 2011.
Her credentials include Ministry of Health–approved certified prolotherapy training. She has taught Prolotherapy and PRP (2022) and Knee Prolotherapy and Campinject (2019). She also taught GETAT and Dextrose Prolotherapy (2018) and ISPRM Ultrasound (2009). She has additional training in musculoskeletal ultrasound, neural therapy, lumbar injections and manipulation, and botulinum toxin treatment for the spastic hand. She attended the Euro‑Mediterranean PRM School in Italy (2010). She is a member of the Turkish Society of PM&R, the Turkish Society for Research and Fight Against Rheumatism, the Association of PM&R Specialists of Türkiye, the Spinal Cord Diseases Association, and the Ankara Medical Chamber.
Professor Kyzas completed his PhD thesis in H&N Cancer with Honours (Αριστα), producing several highly cited influential publications. He has published > 70 scientific papers in high impact journals and has > 6000 citations.
Following his studies, Professor Kyzas has undertaken postgraduate training in the UK and was successful in securing a very competitive training post in the UK Higher Specialty Training Programme for Oral and Maxillofacial Surgery. He was trained in some of the biggest University Teaching hospitals in the North West of the UK. He has been awarded the Certificate of Completion of Training (CCT) in Oral and Maxillofacial Surgery by the General Medical Council (GMC). Subsequently, he was successful in securing one of the very few and prestigious UK-wide Training Interface (TIG) Fellowships in Head and Neck Surgical Oncology. He has successfully completed his fellowship and was awarded the subspecialty of Head and Neck Surgery by the Joint Committee of Surgical training (JCST).
In 2014 he has been appointed as a permanent substantive Consultant in Oral and Maxillofacial/Head and Neck Surgery in Manchester. He has treated hundreds of patients with Head and Neck cancer, offering state of the art major ablative and reconstructive surgery. He specialises in microvascular free tissue transfer and he has introduced and developed the 3D printer – personalised planning (PSP) reconstructive surgery in his hospital. He led his unit to become a reference centre by having the highest number of successful 3D PSP cases in the UK. Besides head and neck cancer, Professor Kyzas offers treatment to patients with facial skin cancer, oral and maxillofacial trauma, dentoalveolar surgery, orthognathic surgery, salivary gland diseases, facial cosmetic surgery, surgery of the temporomandibular joint, and anything else within the broad spectrum of Oral and Maxillofacial Surgery. He has performed many thousands of surgical procedures and has vast experience in any oral and maxillofacial condition. He has a special interest in the use of laser for oral pathologies and he is the Principal Investigator for an international trial examining the effectiveness of Transoral Laser resection in Ηead and Νeck Cancer. He is a certified microvascular surgeon and has accreditation in advanced trauma life support (ATLS).
Just before the covid pandemic, Professor Kyzas was presented with a unique opportunity to lead on the development of a Head and Neck Cancer Service in Lancashire. Professor Kyzas and his team managed to establish the service within months, and throughout the challenging covid period. The ELHT H&N Unit now produces oncological outcomes that compare favourably with any major H&N unit worldwide. Professor Kyzas has been appointed as the Clinical Director for all cancer services in ELHT, covering population of > 1M people.
In 2021, Professor Kyzas has been awarded the highly prestigious Bronze National Clinical Excellence Award for his overall services in the NHS. He was the youngest consultant to achieve this award and the only Cypriot OMFS surgeon ever to be considered for one.
Professor Kyzas has a long history of involvement in medical research. In 2007 he has completed his PhD thesis which has resulted in several highly cited publications in some of the most prestigious medical journals. He has participated in international collaborations for the improvement of medical research (http://progress-partnership.org/publications) and some of his papers have had a significant impact in improving research methodology. He has given several invited international lectures, and he has presented in national and international conferences. He has been a panel member for the selection committees for trainees in every level in oral and Maxillofacial Surgery in the UK. He is a regular peer-reviewer for many medical journals. He is the Lead trainer for the TIG H&N fellowship for his hospital and the Research Lead for his Deanery. He participates actively in Clinical Research, and he is the Principal Investigator for many clinical trials. He is a faculty member for the «Head and Neck resection tactics and free flap» course run by the Royal College of Surgeons of Edinburgh. He offers themed training in Head and Neck Oncological Surgery to medical students. In 2018 he was awarded the «Surgical Educator Excellence Award» by Health Education North West (HEENW). In the same year, he was nominated as doctor of the year in Northern Care Alliance.
Professor Kyzas is the Chief Investigator of the MANTRA trial, a UK multicentre RCT with multimillion pounds NIHR funding, launched in July 2023. This is the biggest randomised controlled trial ever to be performed in the specialty of OMFS.
As a result of his outstanding clinical and research/academic achievements, Professor Kyzas has been appointed as a visiting Professor in OMFS H&N Surgery at Edge Hill University
In 2018 Professor Kyzas was elected as the Deputy Editor for the British Journal of Oral and Maxillofacial Surgery (BJOMS). In January 2024, Professor Kyzas started his role as Editor in Chief for the BJOMS. This is the first time that a Greek Cypriot has ever been chosen for this highly prestigious role. Professor Kyzas sits in the council of the British Association of Oral and Maxillofacial Surgeons (BAOMS).
Professor Kyzas is a fully accredited medical expert witness and has provided hundreds of medical expert negligence reports (πραγματογνώμονας). In June 2024, Professor Kyzas has completed his Degree in Law with Honours (Άριστα), becoming a member of a very prestigious club of medical professionals with an active interest and certified knowledge in medicolegal practice.
Professor Kyzas is a fully accredited Oral and Maxillofacial Surgeon on the specialist register of the General Medical Council (GMC) UK, the Cyprus Medical Association (Cyprus), and the Cyprus Dental Association (Cyprus). In addition, he is also fully recognised and registered as Oral Surgeon by the General Dental Council (GDC) UK. He is a fellow of the Royal College of Surgeons (FRCSEd), member of the Faculty of Surgical Trainers (MFSTEd), fellow of the British Association of Oral and Maxillofacial Surgeons (BAOMS), member of the Hellenic Society of Head and Neck Oncology (HeSHNO) and member of the European Association of Craniomaxillofacial Surgery (ECAMFS).
Dr. Yan Zhi Ping is the Director of the Radiology Department at Xiamen Humanity Hospital. He graduated from the First Military Medical University. He has authored more than 30 papers. He has edited and contributed to several monographs. He received a Fujian Provincial Third Prize for Science and Technology Progress and two Xiamen Municipal Second Prizes. His expertise includes CT and MRI of the central nervous system, musculoskeletal system, thoracic, and abdominal diseases. He also focuses on cerebral functional imaging. He is skilled in the early diagnosis and differential diagnosis of lung cancer and brain tumors.
Appointments: Standing Committee Member of the Radiology Branch of the Fujian Association of Integrative Medicine. Standing Committee Member of the Fujian Radiological Society. Vice Chairman of the Xiamen Radiological Society. Vice Chairman of the Radiology Branch of the Xiamen Medical Doctor Association. Deputy Director of the Xiamen Radiology Quality Control Center.
Associate Professor of General and Bariatric Surgery. Specializes in laparoscopic (minimally invasive) surgery.