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Prof. Amos Toren, MD, PhD, MHA, is a pediatric hemato-oncologist and BMT specialist. He served as Director of Pediatric Hemato-Oncology and BMT at Sheba Medical Center.
He is board certified in Pediatrics, Pediatric Hemato-Oncology, and Bone Marrow Transplantation. He holds a PhD in Human Genetics. He was Head of the Hematology Division at Tel Aviv University for two terms. He is a member of ASH, COG, ESPHI, EBMT, and CIBMTR. He also serves on the Ministry of Health Cord Blood Committee.
He led one of Israel’s most advanced pediatric oncology and BMT programs. The program treated children and young adults. His focus includes leukemia and lymphoma, immunodeficiencies, and rare cancers. He specializes in BMT and CAR T-cell therapy.
His translational research covers CAR T cells, cytokine-induced killer cells, pediatric brain tumors, and targeted therapies. He has worked with St. Anna, the NIH, and St. Jude. His publications include studies on pediatric SCT prophylaxis and PARP resistance.
Professor Pnina Langevich is a rheumatologist and immunologist with over 40 years of experience. She leads the National Center for Rheumatology and Autoimmune Diseases at Sheba Medical Center. Forbes Israel has repeatedly named her among the country’s top doctors.
She is an expert in rheumatoid arthritis, osteoarthritis, joint diseases, systemic lupus erythematosus, scleroderma, and complex autoimmune disorders. She treats severe, treatment‑resistant cases using advanced diagnostics and personalized therapy.
She trained in rheumatology and internal medicine at Sheba. She combines patient care with research on new therapies. She served for 12 years as Vice President of the World Association of Rheumatologists. She is Editor‑in‑Chief of Lupus and a member of the Israeli Medical Association and the International Association of Rheumatologists.
Rambam Medical Center diagnoses myasthenia gravis through rapid antibody testing and advanced neurophysiological studies. Treatment includes pyridostigmine, immunosuppressants, and biological therapies. The center specializes in robotic thymectomy for long-term remission. Specialized clinics reduce waiting times for critical immunological panels and imaging.
Bookimed Expert Insight: While Rambam is a hub for Northern Israel, patients seeking specialized neuro-immunology often compare it with Sourasky Medical Center. Sourasky treats over 400,000 patients annually and holds JCI accreditation. Dr. Dan Kaspy at Sourasky specializes in complex immunological cases. Choosing between Haifa and Tel Aviv often depends on the urgency of robotic surgical availability.
Patient Consensus: Patients suggest requesting an EMG and antibody panel immediately to speed up the diagnosis. Many note that choosing early surgical thymectomy often leads to better results than relying solely on medication.
Surgery is a standard treatment for specific Myasthenia Gravis patients in Israel. Regional guidelines officially recommend thymectomy to improve long-term outcomes. This surgical removal of the thymus gland serves patients with thymic tumours or acetylcholine receptor antibodies. Surgeons often perform the procedure within 2 years of diagnosis.
Bookimed Expert Insight: Israeli medical hubs like Sourasky Medical Center manage high patient volumes with over 400,000 annual visits. Data shows senior specialists often lead the way. For example, Prof. Pnina Langevich has over 40 years of experience in immunology. This deep expertise is vital for Myasthenia Gravis. Large centres combine surgical precision with advanced autoimmune care to reduce risks during recovery.
Patient Consensus: Patients note that surgery in Israel is case-specific rather than a first-line treatment for everyone. They emphasise that high-volume specialist teams and ICU support are vital for managing neuromuscular cases safely.
Israeli hospitals manage myasthenic crises through rapid-acting immunotherapies and emergency neurointensive care. Standard protocols at centres like Sourasky Medical Center prioritise respiratory stabilisation and plasma exchange. Cases failing standard care are escalated to advanced targeted biologics under fast-track national clinical guidelines.
Bookimed Expert Insight: Israeli neurology departments operate with high integration between emergency units and autoimmune specialists. Dr Pnina Langevich at Sheba Medical Center leads the National Center for Rheumatology and Autoimmune Diseases. This centralisation ensures patients in crisis bypass general wards, reaching specialised immunology experts who manage over 400,000 international cases annually across Israel’s top-ranked hospitals.
Patient Consensus: Patients emphasize treating symptoms like swallowing difficulty or a weak cough as immediate emergencies. Support in Israel focuses on rapid ICU admission while carefully avoiding medications like magnesium that can worsen muscle weakness.
Israeli medical centres diagnose Myasthenia Gravis through integrated clinical exams, antibody serology, and neurophysiological studies. JCI-accredited facilities like Sourasky Medical Center provide specialist neuro-immunology panels. This multi-step process identifies specific molecular phenotypes. Results typically guide treatment within 5 to 7 days.
Bookimed Expert Insight: Israeli neuro-immunology units often consolidate diagnostics into a single-week pathway. Sourasky Medical Center performs 34,000 operations annually. This high volume allows specialists like Dr Dan Kaspy to differentiate MG from mimicking rare autoimmune conditions. Patients receive a definitive subtype classification used for targeted therapy.
Patient Consensus: Patients note symptoms are often mistaken for general fatigue before a specialist evaluation. Many suggest keeping a video diary of drooping eyelids to help neurologists in Israel confirm the diagnosis.
Israel maintains standardised national protocols for treating Myasthenia Gravis (MG). These expert-developed guidelines integrate international clinical metrics. They bridge global scientific evidence with the local health system. Protocols ensure uniform diagnostic roadmaps, antibody testing, and structured medication pathways across major centres.
Bookimed Expert Insight: Israeli protocols are notably precise regarding biologic therapy. Specialists may trigger high-efficacy biologics immediately if patients have required mechanical ventilation twice within one year. This structured approach at centres like Sourasky Medical Center ensures patients with intensive cases receive advanced medication without lengthy trial delays.
Patient Consensus: Patients find that Israeli care aligns closely with global evidence-based standards. They note that specialist neurologists manage treatment instead of GPs, with consistent access to therapies like plasmapheresis and rituximab.
Israel treats Myasthenia Gravis using a tiered medical protocol funded by the national health basket. Primary choices include pyridostigmine for symptom relief and corticosteroids for immune control. Advanced biologics like rituximab and efgartigimod are available at JCI-accredited centres like Sourasky Medical Center for refractory cases.
Bookimed Expert Insight: Israeli neurology units often coordinate across departments, such as rheumatology and immunology. Dr Pnina Langevich at Sheba Medical Center has over 40 years of experience in autoimmune diseases. This deep expertise ensures patients transition safely from fast-acting steroids to long-term immunosuppressants with high success rates.
Patient Consensus: Patients note that pyridostigmine helps with daily energy. They also emphasise that preparing for steroid side effects in Israel helps manage the transition to long-term immune control.
Patients must manage heat, physical overexertion, and specific medications to prevent a myasthenic crisis. High temperatures reduce nerve-to-muscle signaling stability. Israeli specialists often manage cases using plasmapheresis and immunotherapies. Pacing activities and avoiding magnesium-based supplements help maintain muscle strength and prevent sudden respiratory or swallowing difficulties.
Bookimed Expert Insight: Israeli neurology departments, such as Sourasky Medical Center, focus heavily on personalised therapy plans. This is vital because adrenaline from stress often masks symptoms temporarily. Patients may experience a rebound flare once tension drops. Specialists like Prof Pnina Langevich, who has over 40 years of experience, emphasise tracking these hormonal and emotional shifts to prevent unexpected relapses during treatment.
Patient Consensus: Patients in Israel emphasise viewing stress as a physical trigger and advise resting before feeling depleted. They suggest sipping cold drinks during meals and using air conditioning to manage bulbar symptoms and heat-induced flares.