Pediatric CAR- for Multiple Myeloma at Sheba Hospital

• CAR-T細胞療法
• 心電図（ECG）
• 血液検査
• 胸部X線
• HIV抗体検査
• B型肝炎コア抗体検査
• 抗HCV抗体検査
• 心エコー図検査
• 全血球計算（CBC）
• 生化学血液検査
• PET/CT
• 腫瘍専門医との診察
• 血液専門医へのコンサルテーション
• 免疫専門医への相談
• 循環器科医への相談
• 小児血液専門医との相談
• 小児科医との相談
• 腫瘍血液専門医との診察
• 頭部MRI
• 生検
• 腫瘍マーカーおよび蛋白分画を含む全血球算定

• 21 日 病院で

• 空港－クリニック－空港間の送迎

Sheba Pediatric CAR-T Program for Multiple Myeloma

At Sheba Medical Center, children and young patients with multiple myeloma have access to one of the most advanced and trusted CAR-T therapy programs in the world. While multiple myeloma is more common in adults, Sheba provides highly specialized care for young and complex cases, including relapsed or treatment-resistant disease.

A Personalized Treatment Designed for Each Patient

CAR-T therapy uses the patient’s own immune system to recognize and destroy cancer cells. For patients with multiple myeloma, this innovative approach offers a highly targeted option when standard treatments are no longer effective.

At Sheba, the entire CAR-T process is performed on-site, ensuring speed, precision, and optimal cell quality:

Apheresis – collection of the patient’s T-cells
Cell Engineering – genetic modification at Sheba’s Advanced Biotherapy Center
Infusion – reintroduction of modified cells to target myeloma cells

Because no steps are outsourced, treatment can begin quickly and is typically completed within ~10 days. CAR-T functions as a “living therapy,” continuing to work in the body and offering the potential for long-term disease control and remission.

Expert Pediatric Leadership and Care

The program is led by Prof. Amos Toren, a globally recognized expert in pediatric hemato-oncology and cellular therapies, with decades of experience and over 1,500 bone marrow transplants performed.

Patients are treated within a highly specialized environment that includes:

Dedicated pediatric and young adult CAR-T units with 24/7 monitoring
A multidisciplinary team of hemato-oncologists, immunologists, and supportive care specialists
A patient- and family-centered approach, ensuring comfort and continuous support
Full international patient services, including travel and care coordination
Advanced Expertise in Complex Cases

Sheba is a global leader in CAR-T therapy, with strong clinical outcomes across hematologic cancers

The program is experienced in managing rare, complex, and high-risk myeloma cases, offering advanced treatment options when other therapies have been exhausted.

Comprehensive Evaluation and Ongoing Support

Each patient undergoes a detailed diagnostic evaluation, including:
advanced imaging, bone marrow testing, genetic and molecular profiling, and full cardiac and pulmonary assessment.

Care is provided in English, Russian, and Arabic, ensuring clear communication and a supportive experience for international families.

A Trusted Place for Advanced Care

By combining cutting-edge science, rapid access to therapy, and compassionate care, Sheba offers one of the most advanced CAR-T programs for multiple myeloma focused on improving outcomes and helping patients return to a better quality of life.

• 専任医療コーディネーター
• 医療旅行手配 — 特別パートナー価格での航空券・ホテル予約
• 医療旅行中の患者擁護