ページ6 - 最高の乳癌医師 - トップ170名の医師

この医師は腫瘍学の専門家であり、肝臓、胆嚢、胃、膵臓、腸管、および乳がんの治療を専門としています。この医師は、Fuda Hospitalで腫瘍専門医としての豊富な経験を持ち、タイのBumrungrad International HospitalおよびRoyal Siriraj Hospitalでも勤務しています。さらに、この医師は中国抗癌協会のメンバーであり、がん治療と研究の進展に対するコミットメントを示しています。

プラット博士は、乳がんの臨床検査結果の臨床応用に長年の研究関心を持つ臨床科学者であり、特に遺伝子発現や乳がんの異なる内因性分子サブタイプの臨床的影響に関心を持っています。また、彼はスペインの乳がん協同組合グループSOLTIで新薬や新しいアプローチの臨床試験を設計し、リードしています。


学歴

• 2003年にバルセロナ大学で医学博士号を取得。
• 2008年にバルデヘブロンがん研究所（VHIO）で医学腫瘍学フェローシップを取得。
• 2008年、ノースカロライナ大学チャペルヒル校（アメリカ）で、チャールズ・M・ペロー教授の研究室でポストドクトラル研究員として活動。

キャリア

• アウグスト・ピ・イ・スニェール生物医学研究所（IDIBAPS）で、固形腫瘍のトランスレーショナルゲノミクスと標的治療のグループの責任者。
• SOLTIの取締役会会長。
• 2018年にBreast International Group (BIG)の執行委員会メンバー。
• Reveal Genomics, SLというスピンオフの共同創設者。
• 3件の発明特許を保持しており、安定した科学的キャリアを証明しています。
• 2012年よりVHIOのトランスレーショナルゲノミクスグループ長。
• Hospital Clínic およびIDIBAPS（2014年）。

出版物

170以上の出版物（H指数51）、合計13,479引用、95件の国際会議での発表を行っています。

教育

• バルセロナ大学のテニュアトラック教授
• ディレクター、乳房病理学 – セノロジーマスターの学位、UB。

Oncogynecologist

Professor Raanan Berger, MD PhD, is a medical oncologist and radiotherapist. He is Director of the Cancer Center at Sheba Medical Center and heads its clinical research unit. He was listed in Forbes Israel’s “Best Doctors” (2025). He leads the genitourinary oncology program with a focus on prostate cancer. His care includes systemic therapy and radiotherapy in a multidisciplinary, patient-centered model.

He is board-certified in oncology. He earned his MD and PhD at Tel Aviv University and completed his clinical training at Sheba. He then completed a postdoctoral fellowship at Dana-Farber/Harvard, focusing on prostate cancer with Dr. Philip Kantoff and molecular oncology in Dr. William C. Hahn’s lab. He is a member of ESMO and ASCO. He has co-authored more than 20 peer-reviewed papers, including studies on outcomes in high- versus very high-risk prostate cancer and on BRCA1/2 in large cohorts.

RESEARCH ACTIVITY

1998–2000 — Conducted research on the genesis of cancer at The Royal Marsden Hospital (England).

PUBLICATIONS

Authored numerous peer-reviewed articles in scientific journals. Selected topics include:

Oncotype Dx Recurrence Score in BRCA1/2 germline mutation carriers with hormone receptor-positive breast cancer.

TP53 missense mutation recurrence in cancer patients of Arab descent.

Adjuvant autologous vaccine for stage III microscopic melanoma: biomarker survival and enhanced response to CTLA-4 blockade.

Prognostic significance of (R)CA15-3 assay in primary breast cancer.

Diagnostic and prognostic value of comparative thymidine kinase 1 (TK1) activity assays in breast cancer patient serum.

Complete remission in a BRCA2 mutation carrier with metastatic pancreatic adenocarcinoma treated with cisplatin.

Autologous vaccine-induced antitumor and self-reactive immune responses in melanoma: impact on patient survival and dependence on MHC class II expression.

PROFESSIONAL AFFILIATIONS

Israeli Society of Clinical Oncology

Israel Medical Association

AWARDS & GRANTS

Cancer Genetics Research Foundation Award

Landau Prize

Judith Segal Memorial Award

Oncologist

Oncologist

Education:

• Faculty of Medicine: Marmara University Faculty of Medicine
• Specialization: Kartal Dr. Lütfi Kırdar Training and Research Hospital
• Minor : Kocaeli University Faculty of Medicine, Medical Oncology.

Professional experiences:

• Oltu State Hospital, Internal Medicine 
• Kocaeli State Hospital, Medical Oncology 
• Marmara University Pendik Training and Research Hospital
• Medistate Kavacik Hospital Medical Oncology.

この医師は、消化器がん、肺がん、婦人科腫瘍の治療において豊富な経験を持っています。彼女は悪性腫瘍性疾患の診断と複雑なケアの専門家として認められています。

悪性腫瘍治療に関する30以上の国内外の科学論文の著者であり、European Society for Medical Oncologyおよびその他の専門協会のメンバーです。

1993年にイスタンブール大学を卒業し、2010年に准教授に昇進し、現在はLIV Hospitalで主要な腫瘍専門医として働いています。彼女の経歴には、Taksim Training and Research Hospital、Kayseri Hospital、Istanbul Hospital、Neolife Medical Centerでの職務が含まれます。

Dr. Abu Shamsiya Rami Nuamanovych is a specialist in general and laparoscopic surgery, oncology, and ultrasound diagnostics. He is a Candidate of Medical Sciences, an associate professor, and a doctor of the highest category. Dr. Nuamanovych is a member of the Ukrainian Association of Bariatric Surgeons and the World Organization of Bariatric Surgeons (IFSO).

He works as a WHO consultant on laparoscopic surgery. He is also President of the Association of Arab Doctors of Ukraine. Dr. Nuamanovych has performed thousands of surgeries, including hernia repairs, bariatric procedures, and cancer operations. His skills are recognized internationally. He speaks English and Arabic fluently.

ジェンティリーニ博士は20年以上の経験を持つ、イタリアの乳がん治療の専門家です。ヨーロッパの腫瘍学研究所で最も経験豊富な乳がん管理の専門家の一人です。サン・ラッファエーレ病院の乳房ユニットを指揮しています。

専門分野

オレステ・ジェンティリーニ博士は、乳房とリンパ節を保護することを目的とした乳がん治療の専門家です。ジェンティリーニ博士は、乳腺がんの発生リスクが高い遺伝的要因を持つ女性に対する予防処置を専門としています。

5,000以上の乳がん手術を施行しています。

職務経験

• 2016年から — イタリアのサン・ラッファエーレ病院の乳がん外科部門で研究部長を務める
• 2016年から — ミラノのヨーロッパ腫瘍学研究所でSOUND（Sentinel node vs Observation after axillary UltraSouND）研究の責任者
• 2015年 — イタリアのサン・ラッファエーレ病院の乳がん外科部門でディレクター
• 2012-2016年 — ミラノのヨーロッパ腫瘍学研究所で主たる研究者（SOUND研究）
• 2007年 — ヨーロッパ腫瘍学研究所（ESMO）の副会長
• 2001-2006年 — ヨーロッパ腫瘍学研究所（ESMO）にてセンロジストの助手
• 1999-2000年 — イタリアのサン・ラッファエーレ病院の一般外科部門で顧問。

教育

• 1993年 — イタリアのミラノ大学医学部で一般医学の学位を取得
• 1999年 — イタリアのミラノ大学医学部で一般外科の専門を修了
• 2001年 — アメリカのNewYork–Presbyterian Hospitalでフェローシップを修了。

科学活動

乳がん治療に関する100以上の論文の著者です。ジェンティリーニ博士は、若年女性や妊娠中の患者における乳がん管理に特に力を入れています。

SOUND研究（Sentinel node vs Observation after axillary Ultra-souND）をコーディネート、早期の乳がん画像診断とその後の適切な治療によって手術を回避することを目的としたプロジェクトです。

組織のメンバーシップ

• EU-BREAST — 創設メンバーであり、副会長
• イタリア国立センロージストと外科医協会（ANISC）の理事会メンバー。

Marmara University Faculty of Medicine, Department of Radiation Oncology Specialization training: 2012 -2016

Marmara University Faculty of Medicine (English) Undergraduate: 2004-2011

Sixteen Numbered Shirvan School (Azerbaijan) High School: 1998 -2004

Areas of Interests

• Breast cancer
• Lung cancer
• Colorectal cancers
• Gynecological and urogenital cancers
• Molecular Oncology

Education:

• Kızıltepe Anatolian High School 2001
• Dicle University Faculty of Medicine 2007
• Istanbul Medeniyet University Göztepe Training and Research Hospital 2014
• Kartal City Hospital 2021
• Associate Professor of Medical Oncology 2023

Experience:

• Liv Hospital Ulus
• Adıyaman University Training and Research Hospital
• Istanbul Umraniye Training and Research Hospital
• Istanbul Umraniye Training and Research Hospital

Research:

• Phase II, Randomized, Open-Label, Multicenter Study to Comparatively Evaluate the Efficacy and Safety of GDC-9545 and Physician-Preferred Endocrine Monotherapy in Previously Treated, Estrogen Receptor Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer Patients, Other ( International), Dr. Murat Ayhan
• Phase III, Randomized, Evaluating the Efficacy and Safety of Palbociclib and Fulvestrant with Gdc-0077 Compared with Placebo in Patients with Pik3ca-Mutant, Hormone Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer. Double Blind, Placebo Controlled Study, Other (International), Dr. Murat Ayhan
• Randomized, Multicenter, Phase Ib/III Study Evaluating the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Atezolizumab Compared to Intravenous Atezolizumab in Patients with Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer, Other (International) Dr. Murat Ayhan
• Randomized, Controlled, Multicenter, Open-Label Study Including Observation Follow-Up for PSMA-PET-Negative Patients, Investigating the Efficacy and Safety of Addition of Apalutamide to Radiotherapy and LHRH Agonist in PSMA-PET-Positive High-Risk Hormone-Sensitive Prostate Cancer Patients, Other (International) Dr. Murat Ayhan
• Biomarker Study to Identify Patients with Advanced Stage Urothelial Cancer and Fibroblast Growth Factor Receptor Gene Aberrations-42756493BLC0002, Other (International), Dr. Murat Ayhan
• Publications:
• Ayhan M, Turan N, Köstek O, et all. Does the efficacy of regorafenib differ in chemotherapy refractory metastatic colorectal cancer patients who had mucinous pathology compared to those who had non-mucinous pathology? Curr Probl Cancer. 2021 Jun;45(3):100670. doi: 10.1016/j.currproblcancer.2020.100670.
• Ayhan M, Odabas H, Turan N, et all. Factors affecting the mortality rate of patients with cancer hospitalized with COVID-19: a single center's experience. J Chemother. 2021 Nov;33(7):499-508. doi: 10.1080/1120009X.2021.1923153.
• Ayhan M, Laçin Ş, Özyükseler DT, et all. Does systemic anti-tumor therapy increase COVID-19 risk in patients with cancer? J Oncol Pharm Pract. 2021 Sep;27(6):1461-1467. doi: 10.1177/10781552211015762.
• Ayhan M, Abamor E, Coban Kokten S, et al. Value of FDG PET/CT in Predicting Pathologic Complete Response After Neoadjuvant Chemotherapy in Locally Advanced Breast Cancer. EJMI 2022;6(2):165–175.
• Ayhan M, Terzioglu K. Experience With Rapid Drug Desensitization With Chemotherapeutics; A SingleCentre Retrospective Study. EJMI 2021;5(3):380–387.
• Doğan A, AYHAN M. Survival analysis of patients with triple-negative breast cancer: a single-center experience. Journal of Oncological Sciences, 8(2), 94-99., Doi: 10.37047/jos.2022-89749
• Terzioğlu K, Ayhan M. Comparative Assessment of Platinum Salts and Taxane Group Hypersensitivity Reactions, The Role of Skin Tests in Diagnosis? J Oncol Pharm Pract. 2021 Nov 30:10781552211050084. doi: 10.1177/10781552211050084.
• Tacar SY, Selcukbiricik F, Yilmaz M, Erturk K, Murat Sarici A, Gulturk I, Ayhan M, Tural D. Nivolumab for metastatic uveal melanoma: a multicenter, retrospective study. Melanoma Res. 2021 Oct 1;31(5):449-455. doi: 10.1097/CMR.0000000000000744.
• Özyurt E, Özçelik S, Sürmeli H, Çelik M, Ayhan M, Özçelik M. Side effects of immune-checkpoint inhibitors: Can multiple side effects be seen in a patient? J Oncol Pharm Pract. 2022 Mar;28(2):462-465. doi: 10.1177/10781552211038136.
• Dülgar Ö, Öven BB, Atcı MM, Arıkan R, Ay S, Ayhan M, Selvi O, Ozyukseler DT, Bayram E, Özcan E, Yasin Aİ, Gümüş M. Is the benefit of using adjuvant capecitabine in patients with residual triple-negative breast cancer related to pathological response to neoadjuvant chemotherapy? Expert Rev Anticancer Ther. 2022 Jul;22(7):773-780. doi: 10.1080/14737140.2022.2076670.
• Hizal M, Bilgin B, Paksoy N, Ayhan M, et all. The real-life efficacy and safety of osimertinib in pretreated advanced non-small cell lung cancer patients with T790M mutation: a Turkish Oncology Group Study. J Cancer Res Clin Oncol. 2022 Jun;148(6):1501-1508. doi: 10.1007/s00432-021-03748-7.
• Volume I, Kucukarda A, Atcı MM, Ayhan M, et all. Efficacy and safety of trastuzumab emtansine in older patients with HER2-positive advanced breast cancer: a real-world study. Tumori. 2022 Feb;108(1):19-25. doi: 10.1177/03008916211037739.
• Dogan I, Ayhan M, Gurbuz M, et all. The frequency and prognostic significance of ABO/Rh blood groups in male breast cancer patients: A multicenter study. Medicine (Baltimore). 2022 Sep 2;101(35):e30147. doi: 10.1097/MD.0000000000030147.
• Ozcelik M, Oyman A, Cil I, Duzgun O, Ozkan OF, Ayhan M. Cytoreductive Surgery versus Systemic Chemotherapy alone in Isolated Peritoneal Carcinomatosis of Colorectal Origin. J Coll Physicians Surg Pak. 2021 Nov;31(11):1308-1313. doi: 10.29271/jcpsp.2021.11.1308.
• Başoğlu T, Sakin A, Erol C, Ayhan M, et all. Real life experienceof patients with locally advanced gastric and gastroesophageal junction adenocarcinoma treated with neoadjuvant chemotherapy: a Turkish oncology group study. J Chemother. 2022 May 17:1-8. doi: 10.1080/1120009X.2022.2073159.
• Özdemir Ö, Zengel B, Yildiz Y, Ayhan M, et all. The effectiveness and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early-stage human epidermal growth factor receptor 2-positive breast cancer: Turkish Oncology Group study. Anticancer Drugs. 2022 Aug 1;33(7):663-670. doi: 10.1097/CAD.0000000000001310.
• Hizal M, Bilgin B, Paksoy N, Ayhan M, et all. The percentage of ALK-positive cells and the efficacy of first-line alectinib in advanced non-small cell lung cancer: is it a novel factor for stratification? (Turkish Oncology Group Study). J Cancer Res Clin Oncol. 2022 Sep 1. doi: 10.1007/s00432-022-04252-2.
• Hizal M, Bilgin B, Paksoy N, Ayhan M, et all. Real-world data on efficacy and safety of first-line alectinib treatment in advanced-stage, ALK-positive non-small-cell lung cancer patients: a Turkish Oncology Group study. Future Oncol. 2022 Jul;18(23):2573-2582. doi: 10.2217/fon-2022-0083.
• Topcu A, Atci MM, Secmeler S, Besiroglu M, Ayhan M, Ozkan M, Bozkurt O, Urakci Z, Ay S, Geredeli C, Yasin AI, Turk HM. Efficacy of trastuzumab and potential risk factors on survival in patients with HER2-positive metastatic gastric cancer. Future Oncol. 2021 Nov;17(31):4157-4169. doi: 10.2217/fon-2021-0398.
• Bilgin B, Sendur MAN, Yucel S, Ayhan M, et all. Real-life comparison of the afatinib and first-generation tyrosine kinase inhibitors in nonsmall cell lung cancer harboring EGFR exon 19 deletion: a Turk Oncology Group (TOG) study. J Cancer Res Clin Oncol. 2021 Jul;147(7):2145-2152. doi: 10.1007/s00432-020-03501-6.
• Atci MM, Akagunduz B, Demir M, Arikan R, Ay S, Ozer M, Ayhan M, Cil I, Demir N, Ozyurt N, Karakaya G, Cevik GT, Onder AH, Selvi O, Sakin A. The impact of adjuvant oxaliplatin and tumor sidedness on the overall survival of stage IIB colon cancer patients: a multicentre study. J Chemother. 2023 Feb;35(1):19-28. doi: 10.1080/1120009X.2022.2040770.
• Tataroglu Ozyukseler D, Ay S, Turan M, Alkan G, Ayhan M, Surmeli H, et al. The Systemic Inflammation Response Index as a Prognostic Marker in Advanced Pancreatic Cancer. EJMI 2022;6(3):367–373.
• Yıldız F, Ayhan M, Demir H, et all. Comparing the efficacy of cabazitaxel in secondline and third-Line treatment of metastatic castration-resistant prostate cancer: a multi-center experience from Turkey. International Journal of Contemporary Medical Research, 7(9), 112-116.,Doi: 10.21276/ijcmr.2020.7.9.30
• Terzioğlu K, Ayhan M. Distribution of allergens detected on patch tests of patients with allergic contact dermatitis and investigation of their atopic background. Annals of Medical Research, 29(5), 422-426., doi: 10.5455/annalsmedres.2021.07.490
• Arikan R, Atci MM, Ay S, Ayhan M, et all Prognostic significance of mucinous histology in left sided metastatic colorectal cancers with wild type RAS and evaluation of backbone chemotherapy regimens. Oncol Lett. 2023 Apr 5;25(5):208. doi: 10.3892/ol.2023.13795.
• Almuradova E, Yalcin S, Arıkan R, Ayhan M, Demir H, Cevik GT, Karaca M, Petekkaya I, Karabulut B. Survival of Patients With Metastatic Rectum Cancer Who Underwent Metastasectomy Following Conversion Chemotherapy Sans Pelvic Radiotherapy: A Turkish Oncology Group Study. Cureus 2023 May 17;15(5):e39119. doi: 10.7759/cureus.39119.
• Topcu A, Besiroglu M, Atci MM, Ayhan M, et all. Second-line Therapy after Trastuzumab Failure in HER2-Positive Metastatic Gastric Cancer: A Real-life Data. EJMI 2023;7(2):153–161. DOI: 10.14744/ejmi.2023.22720
• Book Writing:
• Drug interactions and side effects of targeted agents, Section name: (Small molecule tyrosine kinase inhibitors; ROS-1 targeted therapies (Crizotinib, Seritinib)) (2021)., AYHAN MURAT, Turkish Clinics Journal of Medical Sciences, Editor: Mehmet Aliustaoglu, Publishing number:1, Number of Pages 92, ISBN:978-625-401- 466-6, Turkish
• Approach to gastrointestinal stromal tumors and neuroendocrine tumors, Department name: (Medical approach in primary non-gastrointestinal neuroendocrine tumors) (2020)., AYHAN MURAT, Akademisyen Yayınevi, Editor: Anılır Ender, Number of editions: 1, Number of Pages 382, ISBN: 9786052585719, Turkish
• Internal medicine emergencies, Department name: (Oncological emergencies) (2022)., YILDIRIM SEDAT, AYHAN MURAT, Efe Academic Publishing, Editor: Serdar Olt, Number of editions: 1, Number of Pages 232, ISBN: 978-625-8324-66- 2, Turkish
• Physicians' chemotherapy cancer drug manual 2020, Section name: (Common chemotherapy regimens in clinical practice) (2022)., SÜMBÜL AHMET TANER, ALKAN ALI, AKSOY ASUDE, AYHAN MURAT, et all, Türkiye Klinikleri Journal of Medical Sciences, Editor: EDWAR CHU, VINCENT T. DEVITA, SAADDETIN KILIÇKAP, CEMIL BILIR, SELÇUK SEBER, Number of editions: 1, Number of pages 772, ISBN: 978-625-401-290- 7, Turkish (Book Translation)

Education

Istanbul University Cerrahpaşa Faculty of Medicine, 2002
Istanbul Fatih Sultan Mehmet Training and Research Hospital, Internal Medicine, 2010
Istanbul University Oncology Institute (Çapa), Medical Oncology, 2015
Medipol University Faculty of Medicine, Phytotherapy Education, 2018
University of Health Sciences, Vocational School of Health, Molecular Oncology, PhD Program, PhD, 2023

Experience

University Hospital, Newark, New Jersey, USA, Observer (2003-2004)
Siirt State Hospital, Internal Medicine (2010-2011)
Siirt State Hospital, Medical Oncology (2015)
Bakırköy Dr. Sadi Konuk Training and Research Hospital, Medical Oncology (2015-2018)
Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Medical Oncology, (Professor Doctor) (2018-Present)
Forensic Medicine 3. Specialization Board, Medical Oncology, Full Member (2019-Present)
Liv Hospital, Ulus, Park-time, Medical Oncology (2020-2022)
Şişli Kolan International Hospital, Park-time, Medical Oncology (2022-2023)

Medical Intrests

• Gastrointestinal System Tumours (Esophagus - Stomach and Large Bowel Cancer)
• Hepatobiliary System Tumours (Liver-Biliary Tract and Pancreatic Cancer)
• Breast Cancer
• Lung Cancer
• Genitourinary Cancers
• Immunotherapies and Target Therapies
• Molecular Oncology
• Immunotherapies
• Target Treatments
•  

Awards

2010-YDUS (Subspecialty Examination) 14th place in Turkey
2014- Oncology Institute Days Best Poster Award
2015- Turkish Medical Oncology Society Board Exam Qualification
2015- ESMO (European Society for Medical Oncology) Board Exam Qualification

コンスタンティン・コプチャクは、「膵臓の嚢胞性病変を持つ患者の診断プログラムと外科的治療戦術の合理化」に関する医学博士号の学位論文を擁護しました。Scopusの科学指標ベースに30件の科学論文があります（h指数-2）。ウクライナ国立医学科学院V.I. A.A.シャリモフ名誉外科移植研究所の上級研究員。共同実行者および責任ある実行者として部門の科学的テーマに参加しています。国立癌研究所のリーディングリサーチフェロー。2冊のモノグラフを含む170以上の科学論文の共著者です。